The M157 5.5-liter twin-turbo V8 (577hp in S trim) is regarded as strong, reliable and able to absorb extra power without trouble, with owners reporting well over 100k trouble-free miles. Commenters explicitly steer buyers toward the 2014-2016 M157 cars and away from the 2018-on M177 4.0-liter, citing its rear-main-seal reputation.
M157 5.5L biturbo strength, and contrast with the later M177 4.0L
Mercedes-Benz E63 AMG (W212) · mechanical