Running costs and known weak points — tires, annual service, radiator, transmission

Owners flag the E63 as expensive to run: it eats tires, needs a separate winter wheel set, and MB's insistence on full annual service is costly even at low mileage. A specific vulnerability is the exposed radiator behind the lower grille, which can be punctured by road debris — one owner cites a class-action suit and recommends adding mesh — and buyers are told to confirm the transmission service has been done.